Abstract
Climacteric and postmenopause are life stages marked by profound hormonal changes that significantly impact women’s health, particularly regarding cardiovascular risk. This review discusses the main pharmacological and integrative strategies for managing symptoms during this period, highlighting hormone therapy (HT) in its different formulations, herbal medicine, integrative practices such as yoga and acupuncture, and cognitive behavioral therapy (CBT). The benefits and risks of HT are examined, especially when initiated within the so-called “window of opportunity,” as well as non-hormonal alternatives for patients with contraindications or personal preferences. Recent evidence indicates that the severity of vasomotor symptoms and the timing of treatment initiation directly influence cardiovascular outcomes, emphasizing the importance of individualized approaches. In conclusion, clinical management in postmenopause should address not only symptom relief but also the prevention of adverse cardiovascular events, combining pharmacological and non-pharmacological strategies to enhance women’s quality of life in this stage.
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